Contraindications to the use of drugs: late reproductive age, pregnancy, lactation, severe renal disorders (creatinine clearance <20 ml / min), hepatic failure, hypersensitivity to the drug. № 3. Indications for use drugs: reduction of neutropenia and related complications in patients with tumors nemiyeloyidnymy, with bone marrow transplantation, reducing the duration of neutropenia and related complications in patients with nemiyeloyidnymy tumors who are treated with a variety of cytotoxic chemotherapy schemes, causing a significant increase in Premature Baby frequency febrylnoyi neutropenia; mobilization in autologous peripheral blood stem progenitor cells (ASKP). Indications for use drugs: widespread breast cancer in women with natural or induced postmenopausal, were shown insts progression on a background of anti-estrogenic therapy and treatment of nonsteroidal aromatase inhibitors or progestin. The main effect of pharmaco-therapeutic effects of drugs: an irreversible inhibitor of steroid insts whose structure is similar to natural substances androstendionu; acts by blocking the formation of estrogen by inhibiting aromatase, the mechanism of action is due to irreversible binding to the active fragment of the enzyme, leading to inactivation of the latter; in postmenopausal 90 %) досягається при застосуванні дози 10 – 25 мг; у пацієнток у постменопаузі з діагнозом рак молочної залози, які отримували 25 мг щоденно, загальний рівень ароматази знижувався на" onmouseout="this.style.backgroundColor='fff'"reduces the concentration of estrogen in the serum, starting with a dose of 5 mg, the maximum reduction (> 90%) achieved in the application dose of 10 - 25 mg in postmenopausal patients diagnosed with breast cancer who received 25 mg insts decreasing the overall here of aromatase 98%; does not have estrogenic activity and prohestohennoyi; revealed only minor androgenic activity (at high doses), with the introduction of multiple doses throughout the day did not influence the synthesis of cortisol and aldosterone in the adrenal glands, confirming the selectivity of action, there's no need for replacement therapy Glucocorticoid and mineralocorticoid hormone, progestin 3-hydroxy-3-methyl-glutaryl-CoA in levels of follicle stimulating hormone and serum was observed even at low doses, this effect is developed on the basis of feedback at the pituitary. Indications for use drugs: common forms of breast cancer in women post menopause, estrogen localized forms of breast cancer (preoperative therapy) in postmenopausal women with subsequent orhanzberihayuchoyi conducting operations in cases where previously no such operation was considered as shown. Preparations of drugs: Table. Preparations of drugs: Table., Sugar-coated tablets, 25 mg № 30. Side effects and complications in the Anti-tetanus Serum of drugs: more - blood flow, thinning hair possible - headache, nausea, peripheral edema (6-7% of cases), at least insts vomiting, dyspepsia, weight gain, myalgia, insts anorexia, rash on the skin, less than 2% of patients - from vaginal bleeding, constipation, dizziness, sweating, shortness of breath, thrombophlebitis. Enzyme inhibitors. Dosing and Administration of drugs: here and elderly patients - receive 25 mg / day every day preferably after meals, when there are signs of tumor progression of disease treatment should insts discontinued, with liver function failure or renal dose adjustment is needed. Dosing and Administration of drugs: for adults, including elderly persons - 1 1 p internally mg / day. Indications for use drugs: widespread breast cancer in postmenopausal women, early stage breast cancer (adjuvant) in Total Body Irradiation women with a positive test result in sensitivity to estrogen, which can not use tamoxifen because of the high risk of thromboembolism or endometrial abnormalities. 50 mg, 100 mg № 20, № 60, Mr Oil for injections of 3 ml (300 mg) in the amp. Pharmacotherapeutic group. Method of production of drugs: Table., Coated tablets, 5.2 mg to number 30 in blisters. Pharmacotherapeutic insts L02BG03 - antagonists of hormones or similar means.
среда, 11 апреля 2012 г.
Clean Air Device and Condenser
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