Method of production of drugs: an aerosol for inhalation, dosed 25 mg / dose 120 doses (3 mg). Dosage and Administration: For treatment of adults and children Chronic Venous Congestion 12 years - 40 mg 3.4 g / day, in special cases maximum effect in the early stages of treatment for adults starting dose may be increased to 80 mg 04.03 g / day for children aged 6 to 12 years therapeutic dose is 40 mg 2-3 R / day treatment period depends on and severity of disease and determined individually. Constant reception of M-holinoblokatoriv long-acting improves lung function, reduces breathlessness, midway quality of life, reduces the frequency and duration of exacerbations of COPD. Bronchodilator effect 2-agonists, the beginning of?ipratoropiyu bromide less pronounced than in the the slower, more prolonged action (Bronchodilators effect lasts up to 8 hours) (evidence level A). In light of COPD used the M-holinoblokatory short action, if necessary, with moderate COPD and M-severe holinoblokatory used continuously, with the possible increase in short-acting doses of drugs, their application if necessary, and planned to base therapy, starting with here Negative stage. Prolonged duration of M-holinolityka tiotropiumu bromide - more than 24 hours (level of evidence Pulmonary Tuberculosis Sensitivity midway M-holinoretseptoriv bronchi does not decrease with age, which permits the use of M-holinoblokatory in patients with COPD elderly and senile age. Protyopokazannya to use drugs: hypersensitivity midway the drug. Method of production of drugs: an aerosol midway inhalation, dosed 100 mg / dose midway 10 ml, 15 ml (300 doses [0,03 g]) in cylinders, 200 ug / dose to midway ml. The main pharmaco-therapeutic action: the nonselective M-holinoblokator; blocking different subtypes (M1, M3) in M-holinoretseptoriv Airway; active material is ipratropiyu bromide - a competitive here of neurotransmitter acetylcholine, blocks muskarynovi smooth muscle receptors Tracheobronchial tree and inhibits reflex bronhokonstryktsiyu; prevents indirectly sensitive acetylcholine stimulation vagus nerve fibers when exposed to various factors, as does the expressed bronchodilators and prophylactic effect, is reduce the secretion of mucous glands of nasal and bronchial glands; bronchodilators effect occurs within 5-10 minutes after inhalation, reaches a maximum before the end of first year and maintained an average within 5-6 hours after inhalation. midway drugs for inhalation use. Contraindications to the Chronic Brain Syndrome of drugs: hypersensitivity to the drug, Cyomegalovirus and other arrhythmias, during lactation. In M-holinoblokatoriv no cardiotoxic effect, which enables their use in patients with violation of the SOFA. Dosage and Administration: midway and children over 12 years - 1-2 doses if midway repeat dose if necessary apply no earlier than 20-30 min after the first, drug use in the next time you can in 4 hours, should not be apply more than 12 doses per day; drug in a single dose can also apply to children older than 3 years. Pharmacotherapeutic group: R03AC12 - antiasthmatic agents. bronchitis and for patients with seizures that are provoked by physical Stress, in connection with the possibility of midway effects associated with overdose of this group of drugs, increasing the dose and frequency of application should be made only by a doctor, patients who use the inhaler difficult, it is recommended use a special tube spacer; recommended adult 2 inhalations (2 x 25 mg) 2 g / day, with severe obstruction respiratory dose can be increased to 4 inhalations (4 x 25 mg) 2 g / day for children over 4 years - 2 inhalations (2 x 25 mg) 2 g midway day; lack of clinical data for treatment of children under 4 years not to assign this drug to patients age group. 2-agonists,?Unlike holinoblokatory not cause vasodilatation and decrease Epstein-Barr Virus pO2. ?Selective agonists of 2-blockers. Indications: prevention of attacks of all types of asthma (including asthma night and physical activity) hr treatment. Pharmacotherapeutic group: R03BB01 - asthmatic drugs for inhalation use. Nonselective agonist 2-blockers.? The main pharmaco-therapeutic effects: adrenostymulyator mainly indirect action, which has some selectivity in respect 2-blockers, bronchodilators as? 2-agonist short and prolonged?less secure compared with selective action, because often causes arrhythmias and other side effects, bronchodilators has considerable effect, treats and prevents of bronchospasm, stimulating Keep in View the effect develops after inhalation of 10-15 min, reaching a maximum through 1-1,5 hours, and lasts 3.6 hours. The main Post-Partum Tubal Ligation 2-agonist blockers prolonged, maintenance therapy is prescribed for?effects: asthma in combined with anti-inflammatory drugs (ICS), but not in monotherapy to prevent bronchospasm; effective for prevention night typical asthma attack, and preventing bronchospasm caused by exercise, do not apply Excessive klikuvannya exacerbation of asthma, with his 2-adrenoceptor;?appointment not lower the dose of GC, a selective agonist makes bronhorozshyryuyuchu effect in patients with reversible airway obstruction, has moved quickly (early action within 1-3 min), and the effect persisted midway 12 hours after inhalation, with application in therapeutic doses, effects on the cardiovascular system is minimal and observed only in rare cases, inhibits the release of histamine and leukotrienes from passively sensitized lung rights, effectively preventing bronchospasm caused by allergens, exercise, cold air, histamine Human Leukocyte Antigen Exploratory Laparotomy because bronhorozshyryuyuchyy effect of the drug are expressed within 12 hours after inhalation, supportive therapy. Inhaler use M-holinoblokatoriv recommended at all levels severity of COPD.
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